FANCJ DNA helicase is recruited to the replisome by AND-1 to ensure genome stability
Ana Boavida, Luisa M. R. Napolitano, Diana Santos, Giuseppe Cortone, Nanda Kumar Jegadesan, Silvia Onesti, Dana Branzei, Francesca M. Pisani
This study identifies FANCJ's interaction with AND-1 as critical for replisome recruitment and genome stability, showing that mutations in the CIP box impair this function and contribute to cancer risk.
EMBO Reports · Jan 2, 2024Peer-reviewedMolecular Biology