Molecular BiologyEMBO ReportsPeer-reviewed
FANCJ DNA helicase is recruited to the replisome by AND-1 to ensure genome stability
Ana Boavida, Luisa M. R. Napolitano, Diana Santos…·Francesca M. Pisani
This study identifies FANCJ's interaction with AND-1 as critical for replisome recruitment and genome stability, showing that mutations in the CIP box impair this function and contribute to cancer risk.
11 citations