Author

Luisa M. R. Napolitano

Elettra-Sincrotrone Trieste S.C.p.A.ORCID 0000-0001-9214-7269Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Silvia OnestiiD· 2 shared Alessandro Bregalda· 1 shared Ana BoavidaiD· 1 shared Carlotta GranchiiD· 1 shared Dana BranzeiiD· 1 shared Diana SantosiD· 1 shared Flavio RizzolioiD· 1 shared Francesca M. PisaniiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Silvia OnestiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 8, 2026

Albumin-coated VS1 nanocrystals enable STARD3 inhibition and potentiate fluoropyrimidine therapy in colorectal cancer

Isabella Caligiuri, Alessandro Bregalda, Gloria Saorin…·Flavio Rizzolio

This paper develops albumin-coated nanocrystals to improve the solubility and delivery of the STARD3 inhibitor VS1, enhancing its synergistic effect with 5-FU in colorectal cancer.

DOI 10.64898/2026.07.07.737012

humanbulk RNA-seq

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Molecular BiologyEMBO ReportsPeer-reviewedJan 2, 2024

FANCJ DNA helicase is recruited to the replisome by AND-1 to ensure genome stability

Ana Boavida, Luisa M. R. Napolitano, Diana Santos…·Francesca M. Pisani

This study identifies FANCJ's interaction with AND-1 as critical for replisome recruitment and genome stability, showing that mutations in the CIP box impair this function and contribute to cancer risk.

11 citations

humanexperimental assay

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