Author

Tomoaki Iwayama

The University of OsakaORCID 0000-0002-3405-5822Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Masahide TakedachiiD· 2 shared Chiaki NishizawaiD· 1 shared Dragana KopanjaiD· 1 shared Hiromi Sakashita· 1 shared Hiroshi KurosakaiD· 1 shared Jingyu YeiD· 1 shared Jiro MiuraiD· 1 shared Jun SasakiiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersDevelopmental Biology

Masahide TakedachiORCID

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3 papers

Recent·Most cited

Radicular and periodontal structural defects underlie refractory oral pathology in the adult Hyp mouse model of X-linked hypophosphatemia

Chiaki Nishizawa, Jiro Miura, Tomoaki Iwayama, Miwa Yamazaki, Toshimi Michigami, Kazuaki Miyagawa

This study identifies structural defects in radicular and periodontal tissues in Hyp mice, linking them to refractory dental complications in X-linked hypophosphatemia.

bioRxiv · Apr 30, 2026 · PreprintPathology

A Wnt-responsive fibrocartilage progenitor system coordinates postnatal mandibular condylar cartilage growth

Toshihiro Inubushi, Renshiro Kani, Yutaro Tanida, Yu Usami, Tomoaki Iwayama, Wu Deyang, Jun Sasaki, Jingyu Ye, Shinnosuke Kusano, Yuki Shiraishi, Hiroshi Kurosaka, Dragana Kopanja, Masahide Takedachi, Shinya Murakami, Takashi Yamashiro

The paper identifies a Wnt-responsive fibrocartilage progenitor system that coordinates postnatal mandibular condylar cartilage growth through Foxm1-dependent proliferation and suppression of TGF-β-driven chondrogenic differentiation.

bioRxiv · Mar 27, 2026 · PreprintDevelopmental Biology

Plap-1/Aspn lineage tracing and single-cell transcriptomics reveals cellular dynamics in the periodontal ligament

Tomoaki Iwayama, Mizuho Iwashita, Kazuya Miyashita, Hiromi Sakashita, Shuji Matsumoto, Kiwako Tomita, Phan Bhongsatiern, Tomomi Kitayama, Kentaro Ikegami, Takashi Shimbo, Katsuto Tamai, Masanori A Murayama, Shuhei Ogawa, Yoichiro Iwakura, Satoru Yamada, , Shinya Murakami

This study uses lineage tracing and single-cell transcriptomics to define cell populations and lineage relationships in the periodontal ligament.

Development · Oct 1, 2022Peer-reviewedDevelopmental Biology