BioinformaticsbioRxivPreprint
ITRAP2, a flexible and robust strategy to assign antigen recognition of T-cells in a coupled single-cell TCR-pMHC assay
Grigorii Nos, Amalie Kai Bentzen, Marie Christine Viuff…·Sine Reker Hadrup
ITRAP2 improves TCR-pMHC pairing accuracy by reducing noise and cross-contamination in single-cell data, outperforming existing methods on both in-house and public datasets.