Keerthana Ramanathan

This study shows that Ag-Neo2/15 scaffolds expand antigen-specific T cells with enhanced cytotoxicity and reduced dysfunctionality compared to Ag-IL2/21 scaffolds.

This paper introduces T-Expand, a dextran-based nanoparticle system for T cell expansion that enhances CAR T cell efficacy and reduces manufacturing complexity.

The paper presents a yeast-based system to simulate CD19+ cancers for controlled CAR T cell activation and evaluates antigen density effects.

This study develops antigen-scaffold technology to expand CAR and TCR T cells with improved functionality and efficacy.

This paper develops antigen-dextramers to stain and functionally assess CAR T cells, showing they enable both detection and activation analysis with adjustable antigen density.