Carlos Rodriguez Pardo

This paper introduces T-Expand, a dextran-based nanoparticle system for T cell expansion that enhances CAR T cell efficacy and reduces manufacturing complexity.

This study develops antigen-scaffold technology to expand CAR and TCR T cells with improved functionality and efficacy.

This paper develops antigen-dextramers to stain and functionally assess CAR T cells, showing they enable both detection and activation analysis with adjustable antigen density.

This paper designs de novo pMHC binders using generative models to create T cell-based cancer therapeutics with high specificity and minimal cross-reactivity.

This study investigates magnetogenetic tools to regulate T cell activity, finding they enhance activation with antigen stimulation but deactivate cells without it.