BiochemistrybioRxivPreprint
Structural basis for ATP regulation of human 5-lipoxygenase
Tarvi Teder, Federico Pozzani, Tim Paul Schulte…·Jesper Z. Haeggström
This study presents a cryo-EM structure of human 5-lipoxygenase bound to ATP, revealing how ATP regulates enzyme activity through specific amino acid interactions and conformational changes.
DOI 10.1101/2025.11.26.690380