Author

Tim Paul Schulte

Karolinska University HospitalORCID 0000-0002-7322-8933Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

A. HosseiniiD· 1 shared Adnane AchouriD· 1 shared Andreas Cornelius· 1 shared Benedict J. ChambersiD· 1 shared Denis VillemagneiD· 1 shared Evren AliciiD· 1 shared Federico Pozzani· 1 shared Filip Radom· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. HosseiniORCID

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2 papers

Recent·Most cited

Structural basis for ATP regulation of human 5-lipoxygenase

Tarvi Teder, Federico Pozzani, Tim Paul Schulte, A. Hosseini, Olof Rådmark, Laura Orellana, Jesper Z. Haeggström

This study presents a cryo-EM structure of human 5-lipoxygenase bound to ATP, revealing how ATP regulates enzyme activity through specific amino acid interactions and conformational changes.

bioRxiv · Nov 26, 2025 · PreprintBiochemistry

Development of DARPin T cell engagers for specific targeting of tumor-associated HLA/peptide complexes

Natalia Venetz, Tim Paul Schulte, Sandra Müller, K. Wallden, Stefanie Fischer, Tom Resink, Nadir Kadri, Maria Paladino, Nicole Pina, Filip Radom, Denis Villemagne, Sandra Bruckmaier, Andreas Cornelius, Tanja Hospodarsch, Evren Alici, , Adnane Achour

This study develops DARPin T cell engagers that specifically target HLA/peptide complexes on tumor cells, showing high affinity and specificity through in vitro selection and structural analysis.

iScience · Nov 5, 2025Peer-reviewedSynthetic Biology