Rachel Gleyzer

This study identifies BCL11B as a determinant of chemoresistance in breast cancer, showing it promotes a persister state that TNFα can reverse.

The paper introduces CytoTRACE 2, a deep learning framework to assess cell potency from scRNA-seq data, showing improved performance across multiple datasets and applications.

The paper evaluates the transcriptional fidelity of cancer models using a machine learning tool called CancerCellNet, finding that genetically engineered mice and tumoroids generally show higher fidelity than other model types.