Author
Institute for Stem Cell Biology and Regenerative MedicineORCID 0000-0002-6261-5188Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Zhen Qi, Gunsagar Singh Gulati, Rachel Gleyzer…·Michael F. Clarke
This study identifies BCL11B as a determinant of chemoresistance in breast cancer, showing it promotes a persister state that TNFα can reverse.
Junichi Matsubara, Yong Fuga Li, Sanjay Koul…·Piero D. Dalerba
This study identifies E2F4 as a key regulator of colon cancer resistance to irinotecan by showing its role in drug resistance through shRNA knockdown in PDX models.
Felicia Reinitz, Elizabeth Y. Chen, Benedetta Nicolis di Robilant…·Michael F. Clarke
The paper shows reducing USP16 improves neural precursor cell function and memory in an Alzheimer's model by affecting Cdkn2a and BMP signaling.
Gunsagar Singh Gulati, Shaheen S. Sikandar, Daniel J. Wesche…·Aaron M. Newman
The paper introduces CytoTRACE, a method using transcriptional diversity to predict differentiation states from scRNA-seq data, outperforming existing methods and identifying stem cells and tumor-related genes.
Robert W. Hsieh, Angera H. Kuo, Ferenc A. Scheeren…·Michael F. Clarke
This study identifies CDK19 as a therapeutic target for TNBC by showing its role in tumor growth and metastasis, with minimal impact on normal cells.