Cancer BiologyGenome MedicinePeer-reviewed
Evaluating the transcriptional fidelity of cancer models
Da Peng, Rachel Gleyzer, Wen-Hsin Tai…·Patrick Cahan
The paper evaluates the transcriptional fidelity of cancer models using a machine learning tool called CancerCellNet, finding that genetically engineered mice and tumoroids generally show higher fidelity than other model types.