Sjaak J. de Wit

This study identifies ACE2 as a proviral host factor and TMPRSS2 as a restrictive factor for IBV BD infection in chicken cells.

This study identifies a virulence mechanism in low pathogenic avian influenza viruses where neuraminidase recruits plasminogen to cleave hemagglutinin, enhancing pathogenicity.

The study shows cow mammary gland cells can support replication of multiple IAV strains and are susceptible to co-infection with human and avian IAVs, suggesting the udder may act as a site for viral reassortment.