Rute Maria Pinto

The paper identifies conserved overlapping accessory ORFs in coronavirus N genes and shows that nucleotide and codon biases drive their formation.

This study identifies cis-acting elements that regulate splicing balance between influenza A virus segment 7 mRNA1 and mRNA2, revealing key sequences that influence M1 and M2 protein expression.

This study investigates the evolutionary flexibility of influenza A virus splicing by testing mutations in SD and SA sites, finding that small changes can activate alternative splicing and produce viable variants with altered ion channel and M1 proteins.

This study shows bovine H5N1 influenza viruses have adapted to efficiently use NeuGc receptors in cattle, enhancing replication without significantly altering zoonotic risk.

This study identifies a virulence mechanism in low pathogenic avian influenza viruses where neuraminidase recruits plasminogen to cleave hemagglutinin, enhancing pathogenicity.

Cattle B3.13 H5N1 polymerase gained PB2 M631L and PA K497R, boosting replication in bovine and human cells via better bovine ANP32A use; later PB2 E627K and D740N add activity.

This study identifies an 11th protein, S9-F3, in Tilapia Lake Virus through alternative reading frame translation and characterizes its nuclear export mechanism.

The study shows cow mammary gland cells can support replication of multiple IAV strains and are susceptible to co-infection with human and avian IAVs, suggesting the udder may act as a site for viral reassortment.

This study shows TRIM25 inhibits Influenza A virus by destabilizing its mRNA and is not required for the RIG-I pathway.