Shailendra K. Gupta

The paper identifies Clindamycin as a potential inhibitor of pyroptosis in tumor-associated macrophages by integrating network biology and pharmacophore modeling.

This study identifies ZNF512B as a neuronal-expressed protein that interacts with the NuRD complex to regulate neural-specific gene expression programs.

The paper analyzes extracellular vesicles in amniotic fluid from normal and preeclampsia pregnancies, finding increased CD105+ EVs and antiangiogenic effects in preeclampsia.

The paper develops a MINERVA plugin suite for integrating multi-omics data and performing in silico perturbation experiments on disease maps using RNA-seq datasets from the Atlas of Inflammation Resolution.

The paper describes the development of a computational knowledge repository, the COVID-19 Disease Map, which curates SARS-CoV-2 virus-host interaction mechanisms and provides tools for their analysis and application.