Charles G. Bailey

ZNF185 expression is negatively regulated by CTCF and promotes endometrial cancer growth

This study identifies ZNF185B as a novel isoform of ZNF185 that is upregulated in CTCF-depleted endometrial cancer cells and promotes cancer cell proliferation.

Enhancing adeno-associated virus cellular entry through receptor engineering

This study investigates the molecular mechanisms of AAV receptor AAVR and AAVR2, identifies functional motifs, and demonstrates enhanced AAV entry through engineered receptors.

The ZNF512B-NuRD complex co-ordinates a neural-specific gene expression program

This study identifies ZNF512B as a neuronal-expressed protein that interacts with the NuRD complex to regulate neural-specific gene expression programs.

Intrinsically Disordered Regions Define Unique Protein Interaction Networks in CHD Family Remodelers

The paper identifies unique protein interaction networks in CHD family remodelers by analyzing intrinsically disordered regions and aggregation-prone regions, revealing their role in transcriptional regulation.

Widespread aberrant alternative splicing despite molecular remission in chronic myeloid leukemia patients

The paper shows that chronic myeloid leukemia patients in molecular remission still have widespread aberrant alternative splicing, unlike normal gene expression and DNA methylation patterns.

Ctcf Haploinsufficiency Mediates Intron Retention in A Tissue-specific Manner

This study investigates the impact of Ctcf haploinsufficiency on alternative splicing across multiple tissues, finding tissue-specific increases in intron retention, particularly in genes related to cytoskeletal organization, splicing, and metabolism.