Ryan J. Corbett

This study identifies miRNA programs in pediatric brain tumors linked to immune states and CAR T-cell therapy responses, highlighting miR-149 as a potential regulator.

The paper analyzes splicing in 729 pediatric brain tumors, identifies splicing-defined subgroups, and highlights CLK1 exon 4 as an oncofetal event linked to tumor prognosis.

The paper introduces OpenPedCan, a harmonized multi-omic dataset of pediatric cancer patients, providing integrated genomic, transcriptomic, and proteomic data for research and clinical applications.

AutoGVP classifies germline variants using ClinVar and modified InterVar criteria, enabling large-scale variant pathogenicity assessment in research.

This study uses snATAC-seq to define regulatory elements and transcription factors controlling gene expression in porcine PBMCs at single-cell resolution.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.