Author

Lei Qian

The University of QueenslandORCID 0000-0002-3480-4248Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Elizabeth Jane CoulsoniD· 2 shared Aanchal SharmaiD· 1 shared Eamonn Michael EelesiD· 1 shared Grace NgiamiD· 1 shared Jürgen FrippiD· 1 shared Kai‐Hsiang ChuangiD· 1 shared Leda Kasas· 1 shared Mark C. BellinghamiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Elizabeth Jane CoulsonORCID

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2 papers

Recent·Most cited

Cholinergic basal forebrain neurons regulate vascular dynamics and cerebrospinal fluid flux

Kai‐Hsiang Chuang, Xiaoqing Alice Zhou, Ying Xia, Zengmin Li, Lei Qian, Eamonn Michael Eeles, Grace Ngiam, Jürgen Fripp, Elizabeth Jane Coulson

The paper shows that cholinergic basal forebrain neurons influence vascular-CSF coupling and glymphatic flux in mice, suggesting a neurovascular mechanism for waste clearance in the brain.

Nature Communications · Jun 23, 2025Peer-reviewedNeuroscience

Cholinergic basal forebrain degeneration due to obstructive sleep apnoeaincreases Alzheimer's pathology in mice

Lei Qian, Leda Kasas, Michael Milne, Oliver Rawashdeh, Nicola Marks, Aanchal Sharma, Mark C. Bellingham, Elizabeth Jane Coulson

This study shows that inducing obstructive sleep apnoea in a mouse model of Alzheimer's disease increases Alzheimer's pathology, including amyloid-beta and inflammatory markers, through mechanisms involving hypoxia and the p75 neurotrophin receptor.

bioRxiv · Mar 12, 2020 · PreprintNeuroscience