Genevieve Housman

The paper examines gene expression evolution in primate immune cells under different conditions, finding that perturbation-responsive genes evolve faster than baseline genes.

The paper identifies KLF16 as an inhibitory regulator of osteogenic differentiation through transcriptomic analysis of human iPSC-derived cells and in vivo validation.

This study uses an in vitro model to compare gene regulation in human and chimpanzee skeletal cells, identifying differentially expressed genes that may contribute to skeletal trait differences.

The paper characterizes gene expression responses to biomechanical strain in an in vitro model of osteoarthritis using iPSC-chondrocytes and identifies inter-individual expression differences in response to mechanical strain.

This study examines DNA methylation patterns in baboon skeletal tissues to understand their evolutionary relationship with osteoarthritis, finding conserved and divergent epigenetic features compared to humans.

This study investigates DNA methylation in skeletal tissues of nonhuman primates to explore its association with femur morphology and species-specific traits.

The paper identifies extensive methylation changes in genes related to facial and vocal anatomy in modern humans compared to ancient humans and chimpanzees.

This study assesses DNA methylation patterns in baboon bone and cartilage to identify associations with osteoarthritis and evaluate evolutionary conservation.