NUDT2 loss defines quantitative limits for dinucleoside polyphosphate action on the cGAS-STING-TBK1 axis
Paul Stanley Weiland, Shivakumar Renuka Dharani, Ekaterina Jalomo-Khayrova…·Gert Bange
This study investigates whether NUDT2 loss and subsequent Ap4A accumulation affects the cGAS-STING-TBK1 pathway, finding that physiological levels of Ap4A do not inhibit the pathway.