Author

Vu Van Loi

Freie Universität BerlinORCID 0000-0001-8570-2607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:E. coli· 2 Organism:human· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Haike AntelmanniD· 4 shared Fabiana BurchertiD· 2 shared Gert BangeiD· 2 shared Huihui Li· 2 shared Lena M. GrassiD· 2 shared Stephanie HimpichiD· 2 shared Agnieszka K. BronowskaiD· 1 shared Antonia Kern· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersMicrobiology

Haike AntelmannORCID

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4 papers

Recent·Most cited

A compact Druantia defense clears phage infections via single-stranded DNA recognition and directional duplex unwinding

Stephanie Himpich, Thomas Gaudin, Lena M. Grass, Huihui Li, Vu Van Loi, Chao Chen, Eberhard Klauck, Philipp F. Popp, Maximilian Feussner, Benno Kuropka, Tarek Hilal, Bernhard Loll, Marc Erhardt, Haike Antelmann, Chase L. Beisel, Markus C. Wahl

This paper describes how the Druantia type III-A defense system in E. coli clears phage infections by recognizing single-stranded DNA and unwinding DNA duplexes directionally.

Cell Reports · Sep 22, 2026Peer-reviewedMicrobiology

The diadenosine tetraphosphate hydrolase YqeK controls fitness, biofilm formation, staphyloxanthin production and virulence in Staphylococcus aureus

Vu Van Loi, Sarah Isabelle Przibilla, Fabiana Burchert, Jan Pané‐Farré, Tobias Busche, Christian Rückert, Gert Bange, Haike Antelmann

This study shows that the YqeK hydrolase regulates Ap4A levels in S. aureus, affecting growth, stress survival, biofilm formation, and virulence.

bioRxiv · Sep 9, 2026 · PreprintMicrobiology

The co-localizing Zorya II, Druantia III, and ARMADA II defense systems on O-island 172 confer synergistic anti-phage defense in enterohemorrhagic Escherichia coli

Huihui Li, Vu Van Loi, Costanza Borelli, Stephanie Himpich, Michaela Projahn, Lena M. Grass, T.T. Nguyen, M.C. Wahl, Haike Antelmann

This study identifies that the co-localizing Zorya II, Druantia III, and ARMADA II defense systems on O-island 172 in EHEC confer synergistic anti-phage defense, with Druantia III and ARMADA II providing most of the phage resistance.

mBio · Jun 22, 2026Peer-reviewedMicrobiology

Structural basis of quinone-sensing by the MarR-type repressor MhqR in Staphylococcus aureus

Thao Thi-Phuong Nguyen, Paul Stanley Weiland, Vu Van Loi, Stephan Kiontke, Fabiana Burchert, Victor Zegarra, Antonia Kern, Verena Nadin Fritsch, Daniil Baranov, Agnieszka K. Bronowska, Gert Bange, Haike Antelmann

This paper identifies the quinone-binding pocket of SaMhqR and elucidates its mechanism of inactivation through structural and mutational analyses.

mBio · Dec 31, 2025Peer-reviewedMicrobiology