Molecular BiologybioRxivPreprint
The widely used Ucp1-CreEvdr transgene elicits complex developmental and metabolic phenotypes.
Manasi Suchit Halurkar, Oto Inoue, Rajib Mukherjee…·Joan Sánchez-Gurmaches
The paper analyzes the Ucp1-CreEvdr transgenic mouse line and finds it causes complex developmental and metabolic issues independent of its intended genetic manipulation.
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