Qi Guo

This study identifies DNA hypomethylation, not DNA damage, as the primary mechanism of azacytidine and decitabine anti-cancer activity, linking it to chromatin regulators like USP48.

This study uses multiplex proteomics to identify CSF biomarkers of clinical and neuropathological heterogeneity in Lewy body dementia.

STREAM infers enhancer-driven gene regulatory networks from single-cell RNA-seq and ATAC-seq data, showing improved performance in TF recovery and enhancer-gene discovery.