Author

Xun Tu

Max Planck Florida Institute for NeuroscienceORCID 0000-0002-3534-6525Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xun Tu2 papers · Howard Hughes Medical Institute

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1

Frequent Co-Authors

Ryohei YasudaiD· 3 shared Anant JainiD· 2 shared Lesley A. ColganiD· 2 shared Chancellor Gary· 1 shared Elwy Okaz· 1 shared Goksu OziD· 1 shared Heather L. HolmaniD· 1 shared Helena Decker· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Ryohei YasudaORCID

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3 papers

Recent·Most cited

Dual regulation of spine-specific and synapse-to-nucleus signaling by PKCδ during plasticity

Lesley A. Colgan, Paula Parra-Bueno, Heather L. Holman, Xun Tu, Anant Jain, Mariah F. Calubag, Jaime A. Misler, Chancellor Gary, Goksu Oz, Irena Suponitsky-Kroyter, Elwy Okaz, Ryohei Yasuda

This study investigates the role of PKCδ in synaptic plasticity using FLIM-FRET sensors in mouse CA1 neurons, revealing its dual role in local and nuclear signaling.

Journal of Neuroscience · Jun 5, 2023Peer-reviewedNeuroscience

Local autocrine signaling of IGF1 synthesized and released by CA1 pyramidal neurons regulates plasticity of dendritic spines

Xun Tu, Anant Jain, Helena Decker, Ryohei Yasuda

This study shows that IGF1 synthesized and released by CA1 pyramidal neurons triggers autocrine signaling that regulates dendritic spine plasticity in mice.

bioRxiv · Apr 8, 2021 · PreprintNeuroscience

Rac1 is a downstream effector of PKCα in structural synaptic plasticity

Xun Tu, Ryohei Yasuda, Lesley A. Colgan

This study shows PKCα activates Rac1 during structural synaptic plasticity, linking PKC to spine remodeling through a PDZ binding domain.

Scientific Reports · Feb 4, 2020Peer-reviewedNeuroscience