Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiation
Jie Wang, Jun Nishiyama, Paula Parra-Bueno, Elwy Okaz, Goksu Oz, Xiaodan Liu, Tetsuya Watabe, Irena Suponitsky-Kroyter, Timothy E. McGraw, Erzsebet M. Szatmari, Ryohei Yasuda
The paper shows Rab10 inactivation enhances sLTP and AMPAR trafficking, while Rab4 activation has the opposite effect during synaptic plasticity.
eLife · Sep 23, 2025Peer-reviewedNeuroscience