Dual regulation of spine-specific and synapse-to-nucleus signaling by PKCδ during plasticity
Lesley A. Colgan, Paula Parra-Bueno, Heather L. Holman, Xun Tu, Anant Jain, Mariah F. Calubag, Jaime A. Misler, Chancellor Gary, Goksu Oz, Irena Suponitsky-Kroyter, Elwy Okaz, Ryohei Yasuda
This study investigates the role of PKCδ in synaptic plasticity using FLIM-FRET sensors in mouse CA1 neurons, revealing its dual role in local and nuclear signaling.
Journal of Neuroscience · Jun 5, 2023Peer-reviewedNeuroscience