Author

Lesley A. Colgan

Max Planck Florida Institute for NeuroscienceORCID 0000-0003-2089-6820Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Ryohei YasudaiD· 2 shared Xun TuiD· 2 shared Anant JainiD· 1 shared Chancellor Gary· 1 shared Elwy Okaz· 1 shared Goksu OziD· 1 shared Heather L. HolmaniD· 1 shared Irena Suponitsky-Kroyter· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Ryohei YasudaORCID

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2 papers

Recent·Most cited

NeuroscienceJournal of NeurosciencePeer-reviewedJun 5, 2023

Dual regulation of spine-specific and synapse-to-nucleus signaling by PKCδ during plasticity

Lesley A. Colgan, Paula Parra-Bueno, Heather L. Holman…·Ryohei Yasuda

This study investigates the role of PKCδ in synaptic plasticity using FLIM-FRET sensors in mouse CA1 neurons, revealing its dual role in local and nuclear signaling.

14 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceScientific ReportsPeer-reviewedFeb 4, 2020

Rac1 is a downstream effector of PKCα in structural synaptic plasticity

Xun Tu, Ryohei Yasuda, Lesley A. Colgan

This study shows PKCα activates Rac1 during structural synaptic plasticity, linking PKC to spine remodeling through a PDZ binding domain.

34 citations

mouseexperimental assay

𝕏 PostBluesky