Alexander Quaas

This study identifies Miz1/Myc complexes at enhancers as key regulators of neuroendocrine identity in SCLC, showing their role in gene expression and chemosensitivity.

This study identifies gene expression adaptations of metastases to host tissue using single-cell RNA-sequencing and a novel computational approach, revealing liver-specific expression signatures in colorectal cancer metastases.

This study identifies NMD inhibition as a therapeutic strategy for SCLC by enhancing immunogenicity and improving immunotherapy efficacy through increased neoantigen presentation.

The paper uses single cell RNA-sequencing and genome-wide association study data to identify cell types and processes involved in Barrett's esophagus and esophageal adenocarcinoma risk.

The paper identifies a basal-like subtype in esophageal adenocarcinoma associated with relapse after chemoradiation and poor survival.

This paper develops a CNN-based method to predict HER2 status in esophageal cancer tissue microarrays with high accuracy, outperforming manual assessment and reducing the need for costly follow-up tests.