Author

Marek Franitza

University of Cologne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Alexander QuaasiD· 2 shared Axel M. HillmeriD· 2 shared Christiane J. BrunsiD· 2 shared Kerstin BeckeriD· 2 shared Marten C Wenzel· 2 shared Niels H. GehringiD· 2 shared Patrick Sven PlumiD· 2 shared Sascha HoppeiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Alexander QuaasORCID

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Author profile →

4 papers

Recent·Most cited

Gene expression adaptation of metastases to their host tissue

Luise Nagel, Marten C Wenzel, Sascha Hoppe, Mohammad Karimpour, Patrick Sven Plum, Abdossamad Hamoudi, Israt Jahan, S Schmitt, Marek Franitza, Roger Wahba, Marc Bludau, Christiane J. Bruns, Alexander Quaas, Andreas Beyer, Axel M. Hillmer

This study identifies gene expression adaptations of metastases to host tissue using single-cell RNA-sequencing and a novel computational approach, revealing liver-specific expression signatures in colorectal cancer metastases.

iScience · Jul 21, 2026Peer-reviewedCancer Biology

Single cell analysis of Barrett's esophagus and carcinoma reveals cell types conferring risk via genetic predisposition

Marten C Wenzel, Pouria Dasmeh, Patrick Sven Plum, Ann-Sophie Giel, Sascha Hoppe, Marek Franitza, Christoph Jonas, René Thieme, Yue Zhao, Dominik Heider, Claire Palles, Rebecca Claire Fitzgerald, Christiane J. Bruns, Reinhard Buettner, Alexander Quaas, , Axel M. Hillmer

The paper uses single cell RNA-sequencing and genome-wide association study data to identify cell types and processes involved in Barrett's esophagus and esophageal adenocarcinoma risk.

Cell Genomics · Sep 8, 2025Peer-reviewedCancer Biology

Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated transcriptome in human cells

Volker Boehm, Damaris Wallmeroth, Paul O. Wulf, Oliver Popp, Luiz Gustavo Teixeira Alves, Lucie Reinecke, Maximilian Riedel, Emanuel Wyler, Marek Franitza, Kerstin Becker, Karina Polkovnychenko, Simone Del Giudice, Nouhad Benlasfer, Philipp Mertins, Markus Landthaler, Niels H. Gehring

This study rapidly depletes UPF1 in human cells to investigate NMD-regulated transcriptome dynamics, identifying core transcripts and biological processes affected.

Molecular Cell · Sep 1, 2025Peer-reviewedMolecular Biology

SMG1:SMG8:SMG9-complex integrity maintains robustness of nonsense-mediated mRNA decay

Sabrina Kueckelmann, Sophie Theunissen, Jan‐Wilm Lackmann, Marek Franitza, Kerstin Becker, Volker Boehm, Niels H. Gehring

The paper investigates the role of SMG8 and SMG9 in maintaining NMD robustness by analyzing transcriptome-wide changes and UPF1 interactome in human cells with genetic modifications.

bioRxiv · Apr 15, 2024 · PreprintMolecular Biology