Feng Zhang

AgroGem is a transient transformation system for plants that improves CRISPR editing efficiency and enables DNA repair analysis across multiple species.

This study shows heat stress increases mutation rates in plants, with DNA Polymerase λ mediating mutagenesis, particularly in heterochromatic regions and through 1-bp insertions.

This paper develops a tissue culture-free genome editing system in plants using geminivirus vectors, achieving efficient Cas9, Cas12f, and Cas12j expression with reduced cargo size.

This study develops a method using developmental regulators to improve soybean transformation and CRISPR-mediated genome editing efficiency.

This paper develops a synthetic system using wound-induced regulators to regenerate transgenic and gene-edited shoots in planta, bypassing traditional tissue culture methods.

This study shows SARS-CoV-2 can infect brain cells and organoids derived from human induced pluripotent stem cells, leading to cell death and inflammation, and suggests using these models to study the virus's effects on the brain.