Author

Daphne Yau

Children's Hospital of PhiladelphiaORCID 0000-0002-3559-6479Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:rat· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Abigail Ridler· 1 shared Ana Tangari Saredo· 1 shared Batoul HammoudiD· 1 shared Benjamin Bunce· 1 shared Changhong LiiD· 1 shared Charles A. StanleyiD· 1 shared Diana E. StanescuiD· 1 shared Dinesh GiriiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperDevelopmental Biology

Abigail Ridler

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Chromosome 20p11.2 deletions cause congenital hyperinsulinism via the likely disruption of FOXA2

Thomas William Laver, Matthew Neil Wakeling, Richard C. Caswell, Benjamin Bunce, Daphne Yau, Jonna M. E. Männistö, Jayne Houghton, Jasmin J. Hopkins, Michael N. Weedon, Vrinda Saraff, Melanie Kershaw, Engela Magdalena Honey, Nuala Murphy, Dinesh Giri, Stuart Nath, , Sarah Elizabeth Flanagan

The paper identifies chromosome 20p11.2 deletions as a cause of congenital hyperinsulinism by disrupting FOXA2 expression in pancreatic beta-cells.

European Journal of Human Genetics · Apr 11, 2024Peer-reviewedGenetic & Genomic Medicine

Decreased KATP channel activity contributes to the low glucose threshold for insulinsecretion in the early postnatal period

Juxiang Yang, Batoul Hammoud, Changhong Li, Abigail Ridler, Daphne Yau, Junil Kim, Kyoung‐Jae Won, Charles A. Stanley, Toshinori Hoshi, Diana E. Stanescu

The paper shows that decreased KATP channel surface density in early postnatal rat beta-cells lowers the glucose threshold for insulin secretion, which normalizes by postnatal day 14.

Endocrinology · Jun 16, 2021Peer-reviewedDevelopmental Biology