Author

Changhong Li

Children's Hospital of PhiladelphiaORCID 0000-0003-0699-8900Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Diana E. StanescuiD· 2 shared Junil KimiD· 2 shared Juxiang Yang· 2 shared Kyoung‐Jae WoniD· 2 shared Abigail Ridler· 1 shared Batoul HammoudiD· 1 shared Charles A. StanleyiD· 1 shared Daphne YauiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

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10 top collaborators · 37 mutual co-author links

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2 shared papersDevelopmental Biology

Diana E. StanescuORCID

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2 papers

Recent·Most cited

Developmental BiologyEndocrinologyPeer-reviewedJun 16, 2021

Decreased KATP channel activity contributes to the low glucose threshold for insulinsecretion in the early postnatal period

Juxiang Yang, Batoul Hammoud, Changhong Li…·Diana E. Stanescu

The paper shows that decreased KATP channel surface density in early postnatal rat beta-cells lowers the glucose threshold for insulin secretion, which normalizes by postnatal day 14.

27 citationstop 4%

ratbulk RNA-seq

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Developmental BiologybioRxivPreprintFeb 28, 2021

PDX1 directs a core developmentally and evolutionarily conserved gene program in the pancreatic islet

Xiaodun Yang, Jeffrey C. Raum, Junil Kim…·Diana E. Stanescu

The paper identifies a core set of developmentally and evolutionarily conserved PDX1-bound genes in mouse and human pancreas development, showing stable PDX1 binding across ages with context-dependent regulatory roles.

2 citations

mousehuman

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