Author

Juxiang Yang

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:rat· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Diana E. StanescuiD· 3 shared Kyoung‐Jae WoniD· 3 shared Abigail Ridler· 2 shared Batoul HammoudiD· 2 shared Changhong LiiD· 2 shared Charles A. StanleyiD· 2 shared Junil KimiD· 2 shared Toshinori HoshiiD· 2 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersDevelopmental Biology

Diana E. StanescuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Decreased KATP channel activity contributes to the low glucose threshold for insulinsecretion in the early postnatal period

Juxiang Yang, Batoul Hammoud, Changhong Li, Abigail Ridler, Daphne Yau, Junil Kim, Kyoung‐Jae Won, Charles A. Stanley, Toshinori Hoshi, Diana E. Stanescu

The paper shows that decreased KATP channel surface density in early postnatal rat beta-cells lowers the glucose threshold for insulin secretion, which normalizes by postnatal day 14.

Endocrinology · Jun 16, 2021Peer-reviewedDevelopmental Biology

Early postnatal activation of the hypoxia pathway disrupts β-cell function

Juxiang Yang, Batoul Hammoud, Abigail Ridler, Kyoung‐Jae Won, Toshinori Hoshi, Charles A. Stanley, Diana E. Stanescu, Amanda M. Ackermann

This study shows that early postnatal activation of the HIF1A pathway in rats causes hyperinsulinism and reduced β-cell proliferation, potentially increasing diabetes risk.

bioRxiv · Jun 9, 2021 · PreprintDevelopmental Biology

PDX1 directs a core developmentally and evolutionarily conserved gene program in the pancreatic islet

Xiaodun Yang, Jeffrey C. Raum, Junil Kim, Reynold Yu, Juxiang Yang, Gabriella Rice, Changhong Li, Kyoung‐Jae Won, Doris A. Stoffers, Diana E. Stanescu

The paper identifies a core set of developmentally and evolutionarily conserved PDX1-bound genes in mouse and human pancreas development, showing stable PDX1 binding across ages with context-dependent regulatory roles.

bioRxiv · Feb 28, 2021 · PreprintDevelopmental Biology