Author
Children's Hospital of PhiladelphiaORCID 0000-0003-4881-9392Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Assmaa ElSheikh, Yi‐Ying Kuo, Kara E. Boodhansingh…·Show‐Ling Shyng
The paper identifies seven new SUR1 mutations in HI patients that impair KATP channel trafficking and function, showing varied responses to pharmacochaperone rescue.
Juxiang Yang, Batoul Hammoud, Changhong Li…·Diana E. Stanescu
The paper shows that decreased KATP channel surface density in early postnatal rat beta-cells lowers the glucose threshold for insulin secretion, which normalizes by postnatal day 14.
Juxiang Yang, Batoul Hammoud, Abigail Ridler…·Amanda M. Ackermann
This study shows that early postnatal activation of the HIF1A pathway in rats causes hyperinsulinism and reduced β-cell proliferation, potentially increasing diabetes risk.