Author

Klaus Tenbrock

University of BernORCID 0000-0002-3566-227XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Kim OhliD· 2 shared Norbert WagneriD· 2 shared Angela SchippersiD· 1 shared Anja HolziD· 1 shared Arndt BorkhardtiD· 1 shared Bart N. LambrechtiD· 1 shared Bernd Denecke· 1 shared Cécile LibioulleiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Kim OhlORCID

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2 papers

Recent·Most cited

ImmunologyFrontiers in ImmunologyPeer-reviewedJul 24, 2025

CREB REGULATES FOXP3+ST-2+ TREGS WITH ENHANCED IL-10 PRODUCTION

Sudheendra Hebbar Subramanyam, Judit Turyne Hriczko, Saskia Schulz…·Klaus Tenbrock

This study shows that CREB knockout in Foxp3+ Tregs increases IL-10 and ST-2 expression, enhancing their suppressive function and preventing gut inflammation.

7 citations

mousebulk RNA-seq

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Genetic & Genomic MedicineJournal of Clinical InvestigationPeer-reviewedMay 4, 2021

A human multisystem disorder with autoinflammation, leukoencephalopathy and hepatopathy is caused by mutations in C2orf69

Eva Lausberg, Sebastian Gießelmann, Joseph P. Dewulf…·Florian Kraft

The paper identifies mutations in the C2orf69 gene as the cause of a human multisystem disorder characterized by autoinflammation, leukoencephalopathy, and hepatopathy.

23 citations

humanwhole-exome sequencing

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