Norbert Wagner

This study shows that β7 integrin and L-selectin contribute to DDC-induced cholangiopathy in male mice by promoting immune cell infiltration, gut barrier dysfunction, and microbiota shifts.

This study shows that CREB knockout in Foxp3+ Tregs increases IL-10 and ST-2 expression, enhancing their suppressive function and preventing gut inflammation.

This study shows ICAM-1 protects against adipose tissue inflammation and insulin resistance but worsens liver inflammation and fibrosis in mice with diet-induced obesity.

The paper identifies mutations in the C2orf69 gene as the cause of a human multisystem disorder characterized by autoinflammation, leukoencephalopathy, and hepatopathy.