Laurent Cognet

Nanoscale rheological heterogeneity revealed by Single Particle orientation Tracking (SPoT) of ultrashort carbon nanotubes in brain tissue

This paper introduces SPoT, a method to track carbon nanotubes in brain tissue to study nanoscale rheological heterogeneity by analyzing translational and rotational dynamics.

Back-illumination Phase Imaging Enables Nanoscale Drift Stabilization in Non-transparent Biological Tissues

This paper introduces a method for nanoscale drift stabilization in thick non-transparent tissues using back-illumination phase imaging and cross-correlation analysis, enabling high-quality imaging of extracellular structures.

Decoding Amyloid Plaque Penetrability: Exploring Extracellular Space and Rheology2in Plaque-rich Cortex

This study investigates amyloid plaque penetrability and extracellular space rheology in an AD mouse model using imaging techniques, finding heterogeneous diffusivity and dysregulated extracellular matrix around plaques.

Self-Assembled siRNA-Gold Supraclusters Detected at the Single-Molecule Level in the NIR-II Window

This study reports the self-assembly of NIR-II emitting AuNCs guided by siRNA, demonstrating their stability, photoluminescence, and potential for imaging and gene therapy.

Identification of early-stage liver fibrosis by modifications in the interstitial space diffusive microenvironment using fluorescent single-walled carbon nanotubes

This study uses fluorescent single-walled carbon nanotubes to detect early-stage liver fibrosis by analyzing changes in the interstitial space's diffusive properties.