NeurosciencebioRxivPreprint
SREBP2 delivery to striatal astrocytes normalizes transcription of cholesterol biosynthesis genes and ameliorates pathological features in Huntington's disease
Giulia Birolini, Gianluca Verlengia, Francesca Talpo…·Marta Valenza
This study shows that delivering SREBP2 to astrocytes in HD mice restores cholesterol biosynthesis and improves disease symptoms.
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