Author

Chiara Cordiglieri

Istituto Nazionale Genetica MolecolareORCID 0000-0002-2013-0043Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Alejandro Espadas de Arias· 1 shared Andrea D’Angelo· 1 shared Anna Margherita PietroboniiD· 1 shared Barbara RosicarelliiD· 1 shared Barbara SerafiniiD· 1 shared C. Righetti· 1 shared Chiara VascoiD· 1 shared Claudia IannoneiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Alejandro Espadas de Arias

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeted Antisense Oligonucleotide Treatment Rescues Developmental Alterations in Spinal Muscular Atrophy Organoids

Irene Faravelli, Paola Rinchetti, Monica Tambalo, Illia Simutin, Lisa Mapelli, Sara Mancinelli, Matteo Miotto, Mafalda Rizzuti, Andrea D’Angelo, Chiara Cordiglieri, Giulia Forotti, Clelia Peano, Paolo Kunderfranco, Luca Calandriello, Giacomo P. Comi, , Stefania Paola Corti

This study shows that early ASO treatment rescues developmental defects in SMA organoids by restoring SMN levels and correcting splicing defects.

Nature Communications · Dec 21, 2025Peer-reviewedNeuroscience

Regulatory T-cells in multiple sclerosis produce IL-10 in the central nervous system but are activated by Epstein-Barr Virus

Nadia Pulvirenti, C. Righetti, Francesca Clemente, Barbara Serafini, Chiara Cordiglieri, Chiara Vasco, S. Maioli, Anna Margherita Pietroboni, Eugenia Galeota, Barbara Rosicarelli, Claudia Iannone, Milena Alessandra De Riz, Alejandro Espadas de Arias, Tullia De Feo, Luca V. C. Valenti, , Jens Geginat

This study identifies EOMES+Tr1-like regulatory T-cells in MS that produce IL-10 and are activated by EBV, suggesting their impaired function contributes to immune escape.

bioRxiv · Jul 30, 2024 · PreprintImmunology

SREBP2 delivery to striatal astrocytes normalizes transcription of cholesterol biosynthesis genes and ameliorates pathological features in Huntington's disease

Giulia Birolini, Gianluca Verlengia, Francesca Talpo, Claudia Maniezzi, Lorena Zentilin, Mauro Giacca, Paola Conforti, Chiara Cordiglieri, Claudio Caccia, Valerio Leoni, Franco Taroni, Gerardo Rosario Biella, Michele Simonato, Elena F. Cattaneo, Marta Valenza

This study shows that delivering SREBP2 to astrocytes in HD mice restores cholesterol biosynthesis and improves disease symptoms.

bioRxiv · Nov 23, 2020 · PreprintNeuroscience