Claudia Maniezzi

This study investigates the effects of non-ablative radiotherapy on cardiomyocyte electrophysiology and intracellular Ca2+ dynamics in mice, finding dose-dependent changes in ion currents, action potential parameters, and oxidative stress.

This study shows that delivering SREBP2 to astrocytes in HD mice restores cholesterol biosynthesis and improves disease symptoms.

This study shows that striatal cholesterol infusion prevents cognitive decline and improves motor function in HD mice, with dose-dependent benefits and synaptic recovery.