Immuno-functionomics reveals geographical variation and a role for TLR8 in mRNA vaccine responses
Wesley Huisman, Shohreh Azimi, Thi Yen Nhi Nguyen, Alicia C. de Kroon, Karin de Ruiter, Dicky L. Tahapary, Mikhael D. Manurung, Cilia R. Pothast, Yvonne C. M. Kruize, Mirjam H.M. Heemskerk, Taniawati Supali, Leo G. Visser, Anna H.E. Roukens, Maria Yazdanbakhsh, Simon P. Jochems
The study uses spectral flow cytometry to analyze immune function across populations, revealing geographical differences and TLR8's role in mRNA vaccine responses.
iScience · Oct 25, 2025Peer-reviewedImmunology