Author

Hiroto Kikuchi

Harvard UniversityORCID 0000-0002-3601-8435Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Dan Gabriel DudaiD· 2 shared Peigen HuangiD· 2 shared Satoru MoritaiD· 2 shared Tomofumi AndoiD· 2 shared Alexei HernandeziD· 1 shared Atsuyo MoritaiD· 1 shared Aya MatsuiiD· 1 shared Aya MatsuiiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Dan Gabriel DudaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyCancer Immunology ResearchPeer-reviewedNov 8, 2024

Combined blockade of CXCR4 and PD-1 enhances intratumoral dendritic cell activation and immune responses against HCC

Satoru Morita, Pin‐Ji Lei, Kohei Shigeta…·Dan Gabriel Duda

This study shows that blocking CXCR4 and PD-1 together improves dendritic cell activation and immune responses against HCC in mouse models.

31 citationstop 3%

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 20, 2023

Liver fibrosis uncouples tumor control from survival after multikinase inhibitor immunotherapy in hepatocellular carcinoma

Satoru Morita, Tomofumi Ando, Hiroto Kikuchi…·Dan Gabriel Duda

Liver fibrosis limits the survival benefit of multikinase inhibitor immunotherapy in hepatocellular carcinoma by promoting innate immune-mediated hepatotoxicity despite preserved tumor control.

3 citations

𝕏 PostBluesky