Author

Sriram Varahan

Centre for Cellular and Molecular BiologyORCID 0000-0002-3609-4032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dhrumi ShahiD· 3 shared Sudharsan Mathivathanan· 3 shared Ashish ShrivastavaiD· 1 shared Ishvarya Suresh· 1 shared M Adishree· 1 shared Mary Shejo· 1 shared Nikita Rewatkar· 1 shared Pallavi S. Phatak· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

Dhrumi ShahORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A Glycolysis-Calcineurin Regulatory Axis Orchestrates Titan Cell Formation in Cryptococcus neoformans

Pallavi S. Phatak, Sudharsan Mathivathanan, Dhrumi Shah, Ishvarya Suresh, Mary Shejo, Santosh K. Das, Sriram Varahan

This study identifies a glycolysis-calcineurin regulatory axis that controls titan cell formation in Cryptococcus neoformans, linking central carbon metabolism to calcium homeostasis and fungal morphogenesis.

Genetics · Aug 21, 2026Peer-reviewedMicrobiology

Systematic Screening of a Glycolysis-targeting Small-molecule Library Identifies Novel Inhibitors of Fungal Morphogenesis in Candida albicans

Dhrumi Shah, Yogita Martoliya, Sudharsan Mathivathanan, Ashish Shrivastava, Shailendra Asthana, Sriram Varahan

This study identifies two novel glycolysis inhibitors that block fungal morphogenesis in C. albicans by targeting pyruvate kinase, enhancing antifungal susceptibility and reducing virulence.

bioRxiv · Jul 25, 2026 · PreprintMicrobiology

Glycolysis-dependent Sulfur Metabolism Orchestrates Morphological Plasticity and Virulence in Fungi

Dhrumi Shah, Nikita Rewatkar, M Adishree, Siddhi Gupta, Sudharsan Mathivathanan, Sayantani Biswas, Sriram Varahan

This study identifies a glycolysis-dependent sulfur metabolism pathway critical for fungal morphogenesis and virulence in two fungal species.

eLife · Jan 21, 2026Peer-reviewedMicrobiology