Author

Dhrumi Shah

Centre for Cellular and Molecular BiologyORCID 0009-0005-9108-3933Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Sriram VarahaniD· 3 shared Sudharsan Mathivathanan· 3 shared Ashish ShrivastavaiD· 1 shared Ishvarya Suresh· 1 shared M Adishree· 1 shared Mary Shejo· 1 shared Nikita Rewatkar· 1 shared Pallavi S. Phatak· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

Sriram VarahanORCID

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3 papers

Recent·Most cited

MicrobiologyGeneticsPeer-reviewedAug 21, 2026

A Glycolysis-Calcineurin Regulatory Axis Orchestrates Titan Cell Formation in Cryptococcus neoformans

Pallavi S. Phatak, Sudharsan Mathivathanan, Dhrumi Shah…·Sriram Varahan

This study identifies a glycolysis-calcineurin regulatory axis that controls titan cell formation in Cryptococcus neoformans, linking central carbon metabolism to calcium homeostasis and fungal morphogenesis.

1 citationtop 4%

C. elegansbulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintJul 25, 2026

Systematic Screening of a Glycolysis-targeting Small-molecule Library Identifies Novel Inhibitors of Fungal Morphogenesis in Candida albicans

Dhrumi Shah, Yogita Martoliya, Sudharsan Mathivathanan…·Sriram Varahan

This study identifies two novel glycolysis inhibitors that block fungal morphogenesis in C. albicans by targeting pyruvate kinase, enhancing antifungal susceptibility and reducing virulence.

DOI 10.64898/2026.04.23.720332

C. elegansbulk RNA-seq

𝕏 PostBluesky

MicrobiologyeLifePeer-reviewedJan 21, 2026

Glycolysis-dependent Sulfur Metabolism Orchestrates Morphological Plasticity and Virulence in Fungi

Dhrumi Shah, Nikita Rewatkar, M Adishree…·Sriram Varahan

This study identifies a glycolysis-dependent sulfur metabolism pathway critical for fungal morphogenesis and virulence in two fungal species.

DOI 10.7554/elife.109075.3

yeastC. elegans

𝕏 PostBluesky