This study identifies two novel glycolysis inhibitors that block fungal morphogenesis in C. albicans by targeting pyruvate kinase, enhancing antifungal susceptibility and reducing virulence.

DOI 10.64898/2026.04.23.720332

C. elegansbulk RNA-seq

𝕏 PostBluesky

Cell BiologyCell Communication and SignalingPeer-reviewedJun 3, 2026

Mindin mediated αM-Integrin endocytosis activates STAT3 to maintain keratinocyte stemness

Binita Dam, Johan Ajnabi, Tirthankar Saha…·Colin Jamora

The paper shows that Mindin-mediated αM-Integrin endocytosis activates STAT3 to maintain keratinocyte stemness.

DOI 10.1186/s12964-026-02970-5

humanproteomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 27, 2025

Spontaneous cancer regression as inversion of spontaneous cancer progression: Malignant melanoma remission as a case-study towards clinical applicability

Bindu Kumari, Arushi Misra, Ashish Shrivastava…·Prasun K. Roy

This paper investigates spontaneous cancer regression in melanoma, finding that DNA interference, not immunotherapy, is the primary route for tumor elimination, with therapeutic potential through targeting specific pathways.

DOI 10.64898/2025.12.27.696663

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsPeerJPeer-reviewedOct 3, 2019

Structural, functional and molecular dynamics analysis of cathepsin B gene SNPs associated with tropical calcific pancreatitis, a rare disease of tropics.

Garima Singh, Sri Krishna Jayadev Magani, Rinku Sharma…·Ashutosh Singh

The paper analyzes structural and functional effects of CTSB SNVs in tropical calcific pancreatitis using molecular dynamics and simulation tools.

10 citations

humanDNA methylation

𝕏 PostBluesky