David Dolan

The paper sequenced Norwegian farmhouse yeasts to study their genetic diversity and domestication history, finding they form an early diverging lineage with distinct phylogenetic and population genetic characteristics.

This study reanalyzes the phylogenetic position of traditional Norwegian kveik yeast within Saccharomyces cerevisiae, finding it to be an ancient clade closer to the root of the species tree.

The paper identifies NvPOU4 as a terminal selector gene in Nematostella vectensis, showing it is required for terminal differentiation of neural cells but not their initial specification.

The paper generates patient-specific retinal organoids and RPE from RP type 11 patients to show PRPF31 mutations cause retinal-specific splicing defects and structural/functional impairments, which are corrected by in situ gene editing.