Anika J. Friedman

The paper identifies a hidden binding pocket in FabB that allows alternative acyl chain binding, contrasting with FabF's loss of long-chain binding upon mutation.

The paper designs dynamic biosensors for detecting nitazenes and their metabolites using computational methods, achieving low nanomolar detection limits and limited cross-reactivity.

This study analyzes two engineered biosensors based on PYR1 to recognize different ligands, revealing binding mechanisms and computational methods for biosensor design.