Author

Zirui Dong

Chinese University of Hong KongORCID 0000-0002-3626-6500Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Kwong Wai ChoyiD· 2 shared Zhenjun YangiD· 2 shared Andrei Alexeev· 1 shared Bahram Ghaffarzadeh Kermani· 1 shared Chao DongiD· 1 shared Han Ren· 1 shared Hanjie Shen· 1 shared Hanmin Wei· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Kwong Wai ChoyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Prenatal Diagnosis of Fetuses with Increased Nuchal Translucency by Genome Sequencing Analysis

Kwong Wai Choy, Huilin Wang, Mengmeng Shi, Jingsi Chen, Zhenjun Yang, Rui Zhang, Huanchen Yan, Yanfang Wang, Shaoyun Chen, Matthew Hoi Kin Chau, Ye Cao, Olivia YM Chan, Yvonne K. Y. Kwok, Yuanfang Zhu, Min Chen, , Zirui Dong

This study evaluates genome sequencing for prenatal diagnosis of fetuses with increased nuchal translucency, finding it doubles the diagnostic yield compared to standard methods.

Frontiers in Genetics · Aug 16, 2019Peer-reviewedGenomics

Development of Coupling Controlled Polymerizations by Adapter-ligation in Mate-pair Sequencing for Detection of Various Genomic Variants in One Single Assay

Zirui Dong, Xia Zhao, Qiaoling Li, Zhenjun Yang, Yang Xi, Andrei Alexeev, Hanjie Shen, Ou Wang, Jie Ruan, Han Ren, Hanmin Wei, Xiaojuan Qi, Jiguang Li, Xiaofan Zhu, Yanyan Zhang, , Yuan Jiang

This paper introduces a new mate-pair sequencing method called CP-AL that improves DNA-circularization efficiency and reduces contamination, enabling accurate detection of genomic variants.

DNA Research · May 8, 2019Peer-reviewedGenomics