Xiaojuan Qi

Perturbation Curve models continuous transcriptional response trajectories and improves prediction of genetic modulations

PertCurve models continuous transcriptional response trajectories from CRISPR screens, improving prediction of genetic modulations by capturing diverse perturbation strengths and downstream gene behaviors.

Automated Multimodal Correlative Registration for Organelle-Specific Molecular Imaging

The paper introduces an automated AI pipeline for correlating chemical and ultrastructural images to enable organelle-specific molecular imaging in cells and tissues.

Development of Coupling Controlled Polymerizations by Adapter-ligation in Mate-pair Sequencing for Detection of Various Genomic Variants in One Single Assay

This paper introduces a new mate-pair sequencing method called CP-AL that improves DNA-circularization efficiency and reduces contamination, enabling accurate detection of genomic variants.

Efficient long single molecule sequencing for cost effective and accurate sequencing, haplotyping, and de novo assembly

This paper introduces stLFR, a low-cost method for long DNA sequencing that enables accurate variant calling, haplotyping, and de novo assembly.

Comprehensive analysis of immune evasion in breast cancer by single-cell RNA-seq

This study uses single-cell RNA-seq to analyze the tumor microenvironment of breast cancer, revealing cell type diversity and immune evasion mechanisms.