Sean McCracken

Differential Survival of Retinal Ganglion Cell Types Following Branch Retinal Vein Occlusion

In a mouse branch retinal vein occlusion model, retinal ganglion cells die progressively over 14 days. α-RGCs and F-RGCs are lost fastest, and TBR2-positive intrinsically photosensitive RGCs survive best.

A paradoxical relationship between mitochondrial calcium regulation and retinal ganglion cell degeneration after axon damage

This study shows that higher mitochondrial calcium levels predict retinal ganglion cell survival after optic nerve injury, but reducing mitochondrial calcium increases survival, revealing a paradoxical relationship.

Mistargeted retinal axons induce a synaptically independent subcircuit in the visual thalamus of albino mice.

The paper shows that mistargeted retinal axons in albino and EphB1 knockout mice form synaptically isolated subcircuits in the visual thalamus.